Endogenous cannabinoids and appetite

Appetite and Functional Brain Responses to Cannabinoids

Cannabinoids and appetite: food craving and food pleasure.

The ability of Cannabis sativa to promote eating has been documented for many centuries, with the drug reported by its users to promote strong cravings for, and an intensification of the sensory and hedonic properties of food. These effects are now known to result from the actions of cannabinoid molecules at specific cannabinoid receptor sites within the brain, and to reflect the physiological ...

Role of Endogenous Cannabinoids in Synaptic Signaling

Clinical Neuroscience: Elevated endogenous cannabinoids in schizophrenia

CACorresponding Author These authors contributed equally to this study EVIDENCE suggests that cannabinoid receptors, the pharmacologcial target of cannabis-derived drugs, and their accompanying system of endogenous activators may be dysfunctional in schizophrenia. To test this hypothesis, we examined whether endogenous cannabinoid concentrations in cerebrospinal ̄uid of schizophrenic patients ar...

Role of endogenous cannabinoids in synaptic signaling.

Research of cannabinoid actions was boosted in the 1990s by remarkable discoveries including identification of endogenous compounds with cannabimimetic activity (endocannabinoids) and the cloning of their molecular targets, the CB1 and CB2 receptors. Although the existence of an endogenous cannabinoid signaling system has been established for a decade, its physiological roles have just begun to...